Is NMN well absorbed in capsule form?
Research on NMN mainly uses regular powdered NMN, not sublingual or liposomal forms. Studies show that specific dosages, such as 250 mg, are effective even if not all of it is absorbed.
Harvard's Dr. David Sinclair may take up to 1 gram. There is no research on the safety or overconsumption of liposomal NMN, and regular capsules and powders are sufficient for effective absorption.
What is the primary concern with the liposomal delivery of NMN?
The primary concern is that the amount of NMN absorbed through liposomal delivery is significantly higher than regular NMN, which could lead to negative effects at high dosages.
How much greater absorption does liposomal NMN provide compared to regular NMN?
Liposomal NMN can provide 6x (1.5 grams) to 10x (2.5 grams) greater absorption than the same amount of regular NMN.
Why might higher absorption levels of NMN be problematic?
Higher absorption levels can lead to dosages that are much higher than those demonstrated to be beneficial in studies, potentially causing negative effects.
What is the effect of greater absorption at a cellular level with liposomal NMN?
Greater absorption at a cellular level means that cells which may not normally absorb NMN will do so, and cells that would typically absorb less will absorb more. This disrupts the body’s natural homeostatic process.